Contact information
matthew.rushworth@psy.ox.ac.uk
Anne-Marie Honeyman-Tafa
anne-marie.honeyman-tafa@psy.ox.ac.uk
Research groups
Websites
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Wellcome Centre for Integrative Neuroimaging
Research Centre
Matthew Rushworth FRS
MA DPhil
Watts Chair and Professor of Cognitive Neuroscience, Head of Department
- Head of Department
- Wellcome Trust Senior Investigator
Neural mechanisms of decision making and action selection
I am interested in how the brain makes decisions. Every day we make multiple choices about the best course of action to take in a variety of situations. My research is aimed at understanding the brain processes that allow us to work out how good the outcome of a choice might be and which allow us to make decisions between multiple choices.
I have a particular focus on the role played by areas of prefrontal and cingulate cortex. We have found that activity in these brain regions changes as a function of our expectations about how good a choice will be and when a decision is made.
When cognitive processes, such as those involved in decision-making, unfold they involve a number of different brain events. I am also interested in looking at the connexions between brain regions and the interactions they mediate during decision-making and attentional selection.
The lab's focus is on understanding how decision-making mechanisms work in the healthy brain. It is important to understand them because decision-making is such a fundamental aspect of our mental life. In addition, however, we think that some of these processes go awry when people suffer from psychological illnesses.
Key publications
Valuation and decision-making in frontal cortex: one or many serial or parallel systems?
Journal article
Rushworth MFS. et al, (2012), Curr Opin Neurobiol, 22, 946 - 955
Effects of decision variables and intraparietal stimulation on sensorimotor oscillatory activity in the human brain.
Journal article
Gould IC. et al, (2012), J Neurosci, 32, 13805 - 13818
Social network size affects neural circuits in macaques.
Journal article
Sallet J. et al, (2011), Science, 334, 697 - 700
Recent publications
Computational origins of cortical brain circuits for social cognition.
Journal article
Mahmoodi A. and Rushworth MFS., (2026), Nat Rev Neurosci
Implicit learning across varying temporal scales in individuals with and without mood instability.
Journal article
Atkinson LZ. et al, (2026), J Affect Disord, 395
ctivity in human dorsal raphe nucleus signals changes in behavioural policy.
Journal article
Priestley L. et al, (2026), Nat Commun, 17
Humans are more prosocial in poor foraging environments.
Journal article
Vogel TA. et al, (2026), Nat Commun, 17
Interaction and functional specialization across a distributed neural circuit for flexible task control in macaques.
Journal article
Marche K. et al, (2026), Nat Commun, 17