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The selective knockdown of genes using RNA interference, and the analysis of the resultant phenotype using calcium imaging, is proving to be a powerful combination for discovering new genes involved in calcium signalling. This technical note describes the application of this approach to the Drosophila S2 cell line and its derivatives.

Original publication

DOI

10.1007/s10158-006-0025-z

Type

Journal article

Journal

Invert Neurosci

Publication Date

09/2006

Volume

6

Pages

141 - 144

Keywords

Animals, Calcium, Cell Line, Diagnostic Imaging, Drosophila, Genomics, Macrophages, RNA Interference