Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

We report a lesion-symptom mapping analysis of visual speech production deficits in a large group (280) of stroke patients at the sub-acute stage (<120 days post-stroke). Performance on object naming was evaluated alongside three other tests of visual speech production, namely sentence production to a picture, sentence reading and nonword reading. A principal component analysis was performed on all these tests' scores and revealed a 'shared' component that loaded across all the visual speech production tasks and a 'unique' component that isolated object naming from the other three tasks. Regions for the shared component were observed in the left fronto-temporal cortices, fusiform gyrus and bilateral visual cortices. Lesions in these regions linked to both poor object naming and impairment in general visual-speech production. On the other hand, the unique naming component was potentially associated with the bilateral anterior temporal poles, hippocampus and cerebellar areas. This is in line with the models proposing that object naming relies on a left-lateralised language dominant system that interacts with a bilateral anterior temporal network. Neuropsychological deficits in object naming can reflect both the increased demands specific to the task and the more general difficulties in language processing.

Original publication

DOI

10.1016/j.nicl.2015.01.015

Type

Journal article

Journal

Neuroimage Clin

Publication Date

2015

Volume

7

Pages

463 - 475

Keywords

BCoS, CT, Nonword reading, Picture description, Picture naming, Principal component analysis, Sentence production, Sentence reading, Speech production, Stroke, VBM, Adult, Aged, Aged, 80 and over, Brain Mapping, Female, Functional Laterality, Humans, Male, Middle Aged, Principal Component Analysis, Radiographic Image Interpretation, Computer-Assisted, Speech, Stroke, Tomography, X-Ray Computed