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Improving outcomes in sepsis care Paulo Henrique Orlandi Mourao
Gram-negative bacteria (P. aeruginosa) a common cause of sepsis



Sepsis is one of the leading cause of death. The detection and treatment of sepsis has been highlighted as a key area for improvement in the NHS and internationally. A reliable and pragmatic method is needed for measuring and monitoring the progress of sepsis improvement initiatives in the UK. Current improvement programmes are particularly aimed at improving the detection of sepsis which means that we must, first and foremost, identify those patients who are at risk of sepsis which essentially means any patient who has an infection serious enough to require admission.

In collaboration with Patient Safety Collaborative at the Oxford Academic Health Science Network (AHSN), an extensive list of International Statistical Classification of Diseases and Related Health Problems Tenth Revision (ICD-10) codes for bacterial diagnoses than can causes sepsis have been developed and used to identify hospital admissions at risk of sepsis in the Oxford AHSN region. This work will serve as a baseline measurement for local sepsis improvement efforts.

Project aims:

  1. To estimate the number of patients at risk of sepsis on admission to hospital, the associated clinical diagnoses and risk of mortality.
  2. To use this analysis to propose a short pragmatic set of diagnostic codes which could be used to track the progress of sepsis improvement efforts.

For information about the regional programme, see: 


Funded by

Patient Safety Collaborative, Oxford Academic Health Science Network

Research team

This project is led by Dr. Matthew Inada-Kim, in collaboration with Bethan Page, Charles Vincent and the Patient Safety Collaborative at the AHSN.