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We propose a framework for the memory function of spindle oscillations during sleep. In this framework, memories are reinstated by spindle events and further reprocessed during subsequent spindle refractory periods. We posit that spindle refractoriness is crucial for protecting memory reprocessing from interference. We further argue that temporally-coordinated spindle refractory periods across local networks facilitate the consolidation of rich, multimodal representations, and that localized spindle refractoriness optimizes oscillatory interactions that support systems consolidation in the sleeping brain.

More information Original publication

DOI

10.1016/j.tins.2018.09.012

Type

Journal article

Publication Date

2019-01-01T00:00:00+00:00

Volume

42

Pages

1 - 3

Total pages

2

Keywords

consolidation, neural oscillations, reactivation, refractoriness, Animals, Brain, Electroencephalography, Hippocampus, Humans, Memory, Memory Consolidation, Sleep