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In this article, we discuss the complex problem of relating genotype to phenotype and challenge the simple mapping of genes to higher level cognitive modules. We examine various methods that have been used to investigate this relation including quantitative genetics, molecular genetics, animal models, and in-depth psychological and computational studies of developmental disorders. Both single gene and multiple gene disorders indicate that the relationship between genotype and phenotype is very indirect and that, rather than identifying mere snapshots of developmental outcomes, the process of ontogenetic development itself must be taken into account.

Type

Journal article

Journal

Dev Psychobiol

Publication Date

04/2002

Volume

40

Pages

311 - 322

Keywords

Animals, Child, Developmental Disabilities, Female, Genotype, Humans, Male, Mice, Phenotype