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In recent years, diffusion-weighted magnetic resonance imaging (DW-MRI) has been increasingly used to explore the relationship between white matter structure and cognitive function. This technique uses the passive diffusion of water molecules to infer properties of the surrounding tissue. DW-MRI has been extensively employed to investigate how individual differences in behavior are related to variability in white matter microstructure on a range of different cognitive tasks and also to examine the effect experiential learning might have on brain structural connectivity. Using diffusion tensor tractography, large white matter pathways have been traced in vivo and used to explore patterns of white matter projections between different brain regions. Recent findings suggest that diffusion-weighted imaging might even be used to measure functional differences in water diffusion during task performance. This review describes some research highlights in diffusion-weighted imaging and how this technique can be employed to further our understanding of cognitive function.

Original publication

DOI

10.1177/1073858411421218

Type

Journal article

Journal

Neuroscientist

Publication Date

02/2013

Volume

19

Pages

8 - 15

Keywords

Anisotropy, Brain, Brain Mapping, Cognition, Diffusion Magnetic Resonance Imaging, Humans, Individuality, Nerve Fibers, Myelinated