David Bannerman

• Altered balance of excitatory and inhibitory learning in a genetically modified mouse model of glutamatergic dysfunction relevant to schizophrenia.

  Sanderson DJ. et al, (2017), Sci Rep, 7

• The group II metabotropic glutamate receptor agonist LY354740 and the D2 receptor antagonist haloperidol reduce locomotor hyperactivity but fail to rescue spatial working memory in GluA1 knockout mice.

  Boerner T. et al, (2017), Eur J Neurosci, 45, 912 - 921

• Ongoing neurogenesis in the adult dentate gyrus mediates behavioral responses to ambiguous threat cues.

  Glover LR. et al, (2017), PLoS Biol, 15

• Knockout of NMDA-receptors from parvalbumin interneurons sensitizes to schizophrenia-related deficits induced by MK-801.

  Bygrave AM. et al, (2016), Transl Psychiatry, 6

• Searching for cognitive enhancement in the Morris water maze: better and worse performance in D-amino acid oxidase knockout (Dao(-/-)) mice.

  Pritchett D. et al, (2016), Eur J Neurosci, 43, 979 - 989

• Variation in serotonin transporter expression modulates fear-evoked hemodynamic responses and theta-frequency neuronal oscillations in the amygdala.

  Barkus C. et al, (2014), Biol Psychiatry, 75, 901 - 908

• Hemodynamic responses in amygdala and hippocampus distinguish between aversive and neutral cues during Pavlovian fear conditioning in behaving rats.

  McHugh SB. et al, (2013), Eur J Neurosci, 37, 498 - 507

• Modulation of hippocampal dopamine metabolism and hippocampal-dependent cognitive function by catechol-O-methyltransferase inhibition.

  Laatikainen LM. et al, (2012), J Psychopharmacol, 26, 1561 - 1568

• Hippocampal place cells can encode multiple trial-dependent features through rate remapping.

  Allen K. et al, (2012), J Neurosci, 32, 14752 - 14766

• Evaluating the links between schizophrenia and sleep and circadian rhythm disruption.

  Pritchett D. et al, (2012), J Neural Transm (Vienna), 119, 1061 - 1075

• Dissecting spatial knowledge from spatial choice by hippocampal NMDA receptor deletion.

  Bannerman DM. et al, (2012), Nat Neurosci, 15, 1153 - 1159

• Transgenic overexpression of the type I isoform of neuregulin 1 affects working memory and hippocampal oscillations but not long-term potentiation.

  Deakin IH. et al, (2012), Cereb Cortex, 22, 1520 - 1529

• Hippocampal lesions can enhance discrimination learning despite normal sensitivity to interference from incidental information.

  Sanderson DJ. et al, (2012), Hippocampus, 22, 1553 - 1566

• The role of habituation in hippocampus-dependent spatial working memory tasks: evidence from GluA1 AMPA receptor subunit knockout mice.

  Sanderson DJ. and Bannerman DM., (2012), Hippocampus, 22, 981 - 994

• GluN1 hypomorph mice exhibit wide-ranging behavioral alterations.

  Barkus C. et al, (2012), Genes Brain Behav, 11, 342 - 351

• Systemic inflammation induces acute working memory deficits in the primed brain: relevance for delirium.

  Murray C. et al, (2012), Neurobiol Aging, 33, 603 - 616.e3

• Genetic mouse models relevant to schizophrenia: taking stock and looking forward.

  Harrison PJ. et al, (2012), Neuropharmacology, 62, 1164 - 1167

• Fractionation of spatial memory in GRM2/3 (mGlu2/mGlu3) double knockout mice reveals a role for group II metabotropic glutamate receptors at the interface between arousal and cognition.

  Lyon L. et al, (2011), Neuropsychopharmacology, 36, 2616 - 2628

• Close temporal coupling of neuronal activity and tissue oxygen responses in rodent whisker barrel cortex.

  Li J. et al, (2011), Eur J Neurosci, 34, 1983 - 1996

• Dissociations within short-term memory in GluA1 AMPA receptor subunit knockout mice.

  Taylor AM. et al, (2011), Behav Brain Res, 224, 8 - 14

• Functional alterations to the nigrostriatal system in mice lacking all three members of the synuclein family.

  Anwar S. et al, (2011), J Neurosci, 31, 7264 - 7274

• Gap junctions between interneurons are required for normal spatial coding in the hippocampus and short-term spatial memory.

  Allen K. et al, (2011), J Neurosci, 31, 6542 - 6552

• Competitive short-term and long-term memory processes in spatial habituation.

  Sanderson DJ. and Bannerman DM., (2011), J Exp Psychol Anim Behav Process, 37, 189 - 199

• Deletion of the GluA1 AMPA receptor subunit alters the expression of short-term memory.

  Sanderson DJ. et al, (2011), Learn Mem, 18, 128 - 131

• Characterisation of carbon paste electrodes for real-time amperometric monitoring of brain tissue oxygen.

  Bolger FB. et al, (2011), J Neurosci Methods, 195, 135 - 142

• A MOUSE MODEL OF DELIRIUM DURING DEMENTIA: SYSTEMIC INFLAMMATION INDUCES ACUTE WORKING MEMORY DEFICITS IN THE PRIMED BRAIN

  Murray C. et al, (2011), IRISH JOURNAL OF MEDICAL SCIENCE, 180, 25 - 26

• Opposing alterations in anxiety and species-typical behaviours in serotonin transporter overexpressor and knockout mice.

  Line SJ. et al, (2011), Eur Neuropsychopharmacol, 21, 108 - 116

• Deletion of the GluA1 AMPA receptor subunit impairs recency-dependent object recognition memory.

  Sanderson DJ. et al, (2011), Learn Mem, 18, 181 - 190

• Brain tissue oxygen amperometry in behaving rats demonstrates functional dissociation of dorsal and ventral hippocampus during spatial processing and anxiety.

  McHugh SB. et al, (2011), Eur J Neurosci, 33, 322 - 337

• Fos expression in the brains of rats performing an attentional set-shifting task.

  Burnham KE. et al, (2010), Neuroscience, 171, 485 - 495

• INVESTIGATION OF THE ROLE OF CATECHOL-O-METHYLTRANSFERASE(COMT) ON HIPPOCAMPUS-DEPENDENT BEHAVIOUR

  Laatikainen LM. et al, (2010), JOURNAL OF PSYCHOPHARMACOLOGY, 24, A67 - A67

• Spatial working memory deficits in GluA1 AMPA receptor subunit knockout mice reflect impaired short-term habituation: evidence for Wagner's dual-process memory model.

  Sanderson DJ. et al, (2010), Neuropsychologia, 48, 2303 - 2315

• Multiple memory mechanisms? The long and the short of it.

  Bannerman DM. and Sprengel R., (2010), EMBO J, 29, 1790 - 1791

• The Role of Catechol-O-Methyltransferase (COMT) in Modulating Hippocampal Dopaminergic Metabolism and Behaviour

  Laatikainen LM. et al, (2010), BIOLOGICAL PSYCHIATRY, 67, 214S - 215S

• NEUROBIOLOGICAL EFFECTS OF ALTERED 5-HT TRANSPORTER EXPRESSION: IMPLICATIONS FOR DEPRESSION AND ANXIETY

  Sharp T. et al, (2010), IRISH JOURNAL OF MEDICAL SCIENCE, 179, S98 - S99

• Hippocampal NMDA receptors and anxiety: at the interface between cognition and emotion.

  Barkus C. et al, (2010), Eur J Pharmacol, 626, 49 - 56

• Activation of 5-HT(6) receptors facilitates attentional set shifting.

  Burnham KE. et al, (2010), Psychopharmacology (Berl), 208, 13 - 21

• Fractionating spatial memory with glutamate receptor subunit-knockout mice.

  Bannerman DM., (2009), Biochem Soc Trans, 37, 1323 - 1327

• Behavioural characterization of neuregulin 1 type I overexpressing transgenic mice.

  Deakin IH. et al, (2009), Neuroreport, 20, 1523 - 1528

• Impulsive choice in hippocampal but not orbitofrontal cortex-lesioned rats on a nonspatial decision-making maze task.

  Mariano TY. et al, (2009), Eur J Neurosci, 30, 472 - 484

• Enhanced long-term and impaired short-term spatial memory in GluA1 AMPA receptor subunit knockout mice: Evidence for a dual-process memory model (vol 16, 379, 2009)

  Sanderson DJ. et al, (2009), LEARNING & MEMORY, 16, 508 - 508

• A double dissociation between the effects of sub-pyrogenic systemic inflammation and hippocampal lesions on learning.

  Sanderson DJ. et al, (2009), Behav Brain Res, 201, 103 - 111

• Enhanced long-term and impaired short-term spatial memory in GluA1 AMPA receptor subunit knockout mice: evidence for a dual-process memory model.

  Sanderson DJ. et al, (2009), Learn Mem, 16, 379 - 386

• Comparing the role of the anterior cingulate cortex and 6-hydroxydopamine nucleus accumbens lesions on operant effort-based decision making.

  Walton ME. et al, (2009), Eur J Neurosci, 29, 1678 - 1691

• Induction and expression of GluA1 (GluR-A)-independent LTP in the hippocampus.

  Romberg C. et al, (2009), Eur J Neurosci, 29, 1141 - 1152

• Contribution of hippocampal and extra-hippocampal NR2B-containing NMDA receptors to performance on spatial learning tasks.

  von Engelhardt J. et al, (2008), Neuron, 60, 846 - 860

• The contribution of distinct subregions of the ventromedial frontal cortex to emotion, social behavior, and decision making.

  Rudebeck PH. et al, (2008), Cogn Affect Behav Neurosci, 8, 485 - 497

• Mice overexpressing the 5-hydroxytryptamine transporter show no alterations in feeding behaviour and increased non-feeding responses to fenfluramine.

  Pringle A. et al, (2008), Psychopharmacology (Berl), 200, 291 - 300

• NMDA receptor subunit NR2A is required for rapidly acquired spatial working memory but not incremental spatial reference memory.

  Bannerman DM. et al, (2008), J Neurosci, 28, 3623 - 3630

• A role for dorsal and ventral hippocampus in inter-temporal choice cost-benefit decision making.

  McHugh SB. et al, (2008), Behav Neurosci, 122, 1 - 8

• Dorsal hippocampal N-methyl-D-aspartate receptors underlie spatial working memory performance during non-matching to place testing on the T-maze.

  McHugh SB. et al, (2008), Behav Brain Res, 186, 41 - 47

• The role of the GluR-A (GluR1) AMPA receptor subunit in learning and memory.

  Sanderson DJ. et al, (2008), Prog Brain Res, 169, 159 - 178

• A pathway-specific function for different AMPA receptor subunits in amygdala long-term potentiation and fear conditioning.

  Humeau Y. et al, (2007), J Neurosci, 27, 10947 - 10956

• Supersmart mice: surprising or surprised? Theoretical comment on Singer, Boison, Möhler, Feldon, and Yee (2007).

  Sanderson DJ. and Bannerman DM., (2007), Behav Neurosci, 121, 1137 - 1139

• Distinct contributions of frontal areas to emotion and social behaviour in the rat.

  Rudebeck PH. et al, (2007), Eur J Neurosci, 26, 2315 - 2326

• Neuroscience. Remembering the subtle differences.

  Bannerman DM. and Sprengel R., (2007), Science, 317, 50 - 51

• Deletion of glutamate receptor-A (GluR-A) AMPA receptor subunits impairs one-trial spatial memory.

  Sanderson DJ. et al, (2007), Behav Neurosci, 121, 559 - 569

• Calculating the cost of acting in frontal cortex.

  Walton ME. et al, (2007), Ann N Y Acad Sci, 1104, 340 - 356

• Functional organization of the medial frontal cortex.

  Rushworth MF. et al, (2007), Curr Opin Neurobiol, 17, 220 - 227

• Recruitment of parvalbumin-positive interneurons determines hippocampal function and associated behavior.

  Fuchs EC. et al, (2007), Neuron, 53, 591 - 604

• Impaired spatial working memory but spared spatial reference memory following functional loss of NMDA receptors in the dentate gyrus.

  Niewoehner B. et al, (2007), Eur J Neurosci, 25, 837 - 846

• The drugs don't work-or do they? Pharmacological and transgenic studies of the contribution of NMDA and GluR-A-containing AMPA receptors to hippocampal-dependent memory.

  Bannerman DM. et al, (2006), Psychopharmacology (Berl), 188, 552 - 566

• Weighing up the benefits of work: behavioral and neural analyses of effort-related decision making.

  Walton ME. et al, (2006), Neural Netw, 19, 1302 - 1314

• Separate neural pathways process different decision costs.

  Rudebeck PH. et al, (2006), Nat Neurosci, 9, 1161 - 1168

• Amphetamine promotes task-dependent recovery following focal cortical ischaemic lesions in the rat.

  Gilmour G. et al, (2005), Behav Brain Res, 165, 98 - 109

• GluR-A-dependent synaptic plasticity is required for the temporal encoding of nonspatial information.

  Reisel D. et al, (2005), Behav Neurosci, 119, 1298 - 1306

• Differential involvement of serotonin and dopamine systems in cost-benefit decisions about delay or effort.

  Denk F. et al, (2005), Psychopharmacology (Berl), 179, 587 - 596

• Impaired outcome-specific devaluation of instrumental responding in mice with a targeted deletion of the AMPA receptor glutamate receptor 1 subunit.

  Johnson AW. et al, (2005), J Neurosci, 25, 2359 - 2365

• The mesocortical dopamine projection to anterior cingulate cortex plays no role in guiding effort-related decisions.

  Walton ME. et al, (2005), Behav Neurosci, 119, 323 - 328

• Medial septal lesions mimic effects of both selective dorsal and ventral hippocampal lesions.

  Bannerman DM. et al, (2004), Behav Neurosci, 118, 1033 - 1041

• Catechol-o-methyltransferase inhibition improves set-shifting performance and elevates stimulated dopamine release in the rat prefrontal cortex.

  Tunbridge EM. et al, (2004), J Neurosci, 24, 5331 - 5335

• A comparison of GluR-A-deficient and wild-type mice on a test battery assessing sensorimotor, affective, and cognitive behaviors.

  Bannerman DM. et al, (2004), Behav Neurosci, 118, 643 - 647

• Regional dissociations within the hippocampus--memory and anxiety.

  Bannerman DM. et al, (2004), Neurosci Biobehav Rev, 28, 273 - 283

• Catechol-o-methyltransferse (COMT) inhibition improves set shifting performance in the rat

  Tunbridge EM. et al, (2004), BIOL PSYCHIAT, 55, 162S - 162S

• The effects of intracortical endothelin-1 injections on skilled forelimb use: implications for modelling recovery of function after stroke.

  Gilmour G. et al, (2004), Behav Brain Res, 150, 171 - 183

• Amygdala and ventral hippocampus contribute differentially to mechanisms of fear and anxiety.

  McHugh SB. et al, (2004), Behav Neurosci, 118, 63 - 78

• Spatial reference memory in GluR-A-deficient mice using a novel hippocampal-dependent paddling pool escape task.

  Schmitt WB. et al, (2004), Hippocampus, 14, 216 - 223

• Entorhinal cortex lesions disrupt the transition between the use of intra- and extramaze cues for navigation in the water maze (vol 117, pg 588, 2003)

  Oswald CJP. et al, (2003), BEHAVIORAL NEUROSCIENCE, 117, 938 - 938

• GluR-A-Deficient mice display normal acquisition of a hippocampus-dependent spatial reference memory task but are impaired during spatial reversal.

  Bannerman DM. et al, (2003), Behav Neurosci, 117, 866 - 870

• Functional specialization within medial frontal cortex of the anterior cingulate for evaluating effort-related decisions.

  Walton ME. et al, (2003), J Neurosci, 23, 6475 - 6479

• Entorhinal cortex lesions disrupt the transition between the use of intra- and extramaze cues for navigation in the water maze.

  Oswald CJ. et al, (2003), Behav Neurosci, 117, 588 - 595

• A within-subjects, within-task demonstration of intact spatial reference memory and impaired spatial working memory in glutamate receptor-A-deficient mice.

  Schmitt WB. et al, (2003), J Neurosci, 23, 3953 - 3959

• A within-subjects, within-task demonstration of intact spatial reference memory and impaired spatial working memory in glutamate receptor-A-deficient mice

  Schmitt WB. et al, (2003), Journal of Neuroscience, 23, 3953 - 3958

• Ventral hippocampal lesions affect anxiety but not spatial learning.

  Bannerman DM. et al, (2003), Behav Brain Res, 139, 197 - 213

• Learning associations between places and visual cues without learning to navigate: neither fornix nor entorhinal cortex is required.

  Gaffan EA. et al, (2003), Hippocampus, 13, 445 - 460

• The role of rat medial frontal cortex in effort-based decision making.

  Walton ME. et al, (2002), J Neurosci, 22, 10996 - 11003

• Double dissociation of function within the hippocampus: spatial memory and hyponeophagia.

  Bannerman DM. et al, (2002), Behav Neurosci, 116, 884 - 901

• Effects of cytotoxic hippocampal lesions in mice on a cognitive test battery.

  Deacon RM. et al, (2002), Behav Brain Res, 133, 57 - 68

• Anxiolytic effects of cytotoxic hippocampal lesions in rats.

  Deacon RM. et al, (2002), Behav Neurosci, 116, 494 - 497

• Selective cytotoxic lesions of the retrohippocampal region produce a mild deficit in social recognition memory.

  Bannerman DM. et al, (2002), Exp Brain Res, 142, 395 - 401

• The role of the entorhinal cortex in two forms of spatial learning and memory.

  Bannerman DM. et al, (2001), Exp Brain Res, 141, 281 - 303

• The effect of cytotoxic lesions of the hippocampus on recognition memory in the rat: effects of stimulus size.

  Higgs S. et al, (2001), Behav Neurosci, 115, 1193 - 1203

• Contextual fear conditioning is disrupted by lesions of the subcortical, but not entorhinal, connections to the hippocampus.

  Bannerman DM. et al, (2001), Exp Brain Res, 141, 304 - 311

• Faster is not surer--a comparison of C57BL/6J and 129S2/Sv mouse strains in the watermaze.

  Contet C. et al, (2001), Behav Brain Res, 125, 261 - 267

• Rats' processing of visual scenes: effects of lesions to fornix, anterior thalamus, mamillary nuclei or the retrohippocampal region.

  Gaffan EA. et al, (2001), Behav Brain Res, 121, 103 - 117

• Cytotoxic lesions of the hippocampus increase social investigation but do not impair social-recognition memory.

  Bannerman DM. et al, (2001), Exp Brain Res, 138, 100 - 109

• The time course of the hyperactivity that follows lesions or temporary inactivation of the fimbria-fornix.

  Bannerman DM. et al, (2001), Behav Brain Res, 120, 1 - 11

• Conditional discriminations based on external and internal cues in rats with cytotoxic hippocampal lesions.

  Deacon RM. et al, (2001), Behav Neurosci, 115, 43 - 57

• Rats with hippocampal lesions learn about allocentric place cues in a non-navigational task.

  Gaffan EA. et al, (2000), Behav Neurosci, 114, 895 - 906

• Double dissociation of function within the hippocampus: a comparison of dorsal, ventral, and complete hippocampal cytotoxic lesions.

  Bannerman DM. et al, (1999), Behav Neurosci, 113, 1170 - 1188

• Dissociating context and space within the hippocampus: effects of complete, dorsal, and ventral excitotoxic hippocampal lesions on conditioned freezing and spatial learning.

  Richmond MA. et al, (1999), Behav Neurosci, 113, 1189 - 1203

• Intracerebroventricular infusion of the NMDA receptor-associated glycine site antagonist 7-chlorokynurenate impairs water maze performance but fails to block hippocampal long-term potentiation in vivo.

  Bannerman DM. et al, (1997), Neurobiol Learn Mem, 68, 252 - 270

• Distinct components of spatial learning revealed by prior training and NMDA receptor blockade.

  Bannerman DM. et al, (1995), Nature, 378, 182 - 186

• PRIOR EXPERIENCE DISSOCIATES COMPONENTS OF N-METHYL-D-ASPARTATE-DEPENDENT FORMS OF SPATIAL-LEARNING IN THE WATERMAZE

  MORRIS R. et al, (1995), BEHAVIOURAL PHARMACOLOGY, 6, 627 - 627

• Inhibition of nitric oxide synthase does not prevent the induction of long-term potentiation in vivo.

  Bannerman DM. et al, (1994), J Neurosci, 14, 7415 - 7425

• Inhibition of nitric oxide synthase does not impair spatial learning.

  Bannerman DM. et al, (1994), J Neurosci, 14, 7404 - 7414

• Intracerebroventricular injection of a nitric oxide synthase inhibitor does not affect long-term slope potentiation in vivo.

  Bannerman DM. et al, (1994), Neuropharmacology, 33, 1387 - 1397

Recent Publications

• Altered balance of excitatory and inhibitory learning in a genetically modified mouse model of glutamatergic dysfunction relevant to schizophrenia.

  Sanderson DJ. et al, (2017), Sci Rep, 7

• The group II metabotropic glutamate receptor agonist LY354740 and the D2 receptor antagonist haloperidol reduce locomotor hyperactivity but fail to rescue spatial working memory in GluA1 knockout mice.

  Boerner T. et al, (2017), Eur J Neurosci, 45, 912 - 921

• Ongoing neurogenesis in the adult dentate gyrus mediates behavioral responses to ambiguous threat cues.

  Glover LR. et al, (2017), PLoS Biol, 15

• Knockout of NMDA-receptors from parvalbumin interneurons sensitizes to schizophrenia-related deficits induced by MK-801.

  Bygrave AM. et al, (2016), Transl Psychiatry, 6

• Searching for cognitive enhancement in the Morris water maze: better and worse performance in D-amino acid oxidase knockout (Dao(-/-)) mice.

  Pritchett D. et al, (2016), Eur J Neurosci, 43, 979 - 989