One of the most fascinating developments over the past years has been the recognition that the cerebellum is not just involved in motor control and motor learning but that it is engaged in almost all neurological functions including cognitive, emotional and social-psychological functions. This range of functions is reflected by the many diseases that are linked to dysfunction of these cerebellar domains. Mounting evidence suggests a role for the cerebellum in autism. However, the molecular mechanisms linking cerebellar function to autism remain incompletely understood. I will present work from our group that investigates the role of autism genes in the development and function of the cerebellum by integrating experimental developmental neurobiology and computational analyses.
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