Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

Please join us online or in person. An informal reception – with tea, coffee, biscuits and cake – will be held afterwards for those attending in person.



Recordings of neurons in cortical structures in behaving rodents show responses relevant to encoding of space and time for episodic memory and goal directed behaviour. Spatial location is coded by grid cells in entorhinal cortex and place cells in hippocampus (O’Keefe, 1976; Hafting et al., 2005). Grid cells and place cells can also code temporal intervals in a behavioural task, firing at specific time intervals or running distances when a rat runs on a treadmill (Kraus et al., 2013; 2015; Mau et al., 2018). Modeling shows that coding as time cells may arise from exponential decay of neural activity on multiple time scales (Liu et al., 2019). Coding of space could involve both path integration and transformation of sensory input. Coding of location by path integration could involve coding of running speed (Hinman et al., 2016). Inactivation of input from the medial septum impairs the spatial selectivity of grid cells suggesting rhythmic coding of running speed is essential to grid cell firing (Brandon et al., 2011). In addition, transformation of sensory input may be more important for computing location. Recent data from our lab shows coding of environmental boundaries in egocentric coordinates (Hinman et al., 2019; Alexander et al., 2020) that could be combined with head direction to generate allocentric coding of boundaries and spatial location (Bicanski and Burgess, 2018). These different neural mechanisms could mediate the coding of time and spatial location for episodic memory and goal-directed behaviour.


You can find out more about the speaker at



Registration is required to attend online or in person.  

For those attending in person, the event will take place in the Seminar Room on the second floor of New Radcliffe House, followed by an informal reception.

Link to attend online:

Link to attend in person: