How Hippocampal Memory Shapes, and Is Shaped By, Attention
Dr Mariam Aly (Columbia University)
BEACON Seminar Series
Tuesday, 13 October 2020, 3pm to 4pm
Hosted by Nick Myers
We are excited to kick off this term's BEACON seminar series next week with a talk from Mariam Aly (Columbia University). The talk will be on Zoom (link to be circulated shortly). If you would like to arrange a meeting with Mariam, please contact Nick Meyers at firstname.lastname@example.org.
Attention modulates what we see and remember. Memory affects what we attend to and perceive. Despite this connection in behaviour, little is known about the mechanisms that link attention and memory in the brain. One key structure that may be at the interface between attention and memory is the hippocampus. Here, I’ll explore the hypothesis that the relational representations of the hippocampus allow it to critically contribute to bidirectional interactions between attention and memory.
First, I’ll show — in a series of human fMRI studies — that attention creates state-dependent patterns of activity in the hippocampus, and that these representations predict both online attentional behaviour and memory formation. Then, I’ll provide neuropsychological evidence that hippocampal damage impairs performance on attention tasks that tax relational representations, particularly spatial relational representations. Furthermore, cholinergic modulation (from nicotine) may play a role enhancing this form of hippocampal attention and perception. Finally, I’ll demonstrate that hippocampal memories enable preparation for upcoming attentional states, particularly when those attentional states are guided by memory. Together, this line of work highlights the tight links between attention and memory – links that are established, at least in part, by the hippocampus.
Future Michaelmas talks in the BEACON SERIES:
- Tuesday, 20 October, 11:00pm, Laura Bradfield (Sydney)
- Tuesday, 3 November, 1:00pm, with Nadescha Trudel (Oxford)
- Tuesday, 10 November, 1:00pm, with Matthew Gardner (NIH)
- Tuesday, 24 November, 1:00pm, with Andreas Klaus (Champalimaud)
- Tuesday, 8 December, 1:00pm, with Anne Urai (CSHL)
- Tuesday, 15 December, 1:00pm, with Nahid Zokaei (Oxford)