Neuroscience Seminar: Targeting space and time in the human hand knob
Hartwig Siebner (University of Copenhagen)
Wednesday, 05 April 2017, 3pm to 4pm
Large Lecture Theatre, Department of Plant Sciences, South Parks Road, Oxford, OX1 3RB
Transcranial magnetic stimulation (TMS) is widely used to study the physiology of the primary motor hand area (M1-HAND) in humans. In the first part of my talk, I will describe a novel “spatial neuronavigation” approach designed to map the somatotopy of corticomotor representations in the motor hand knob. Using sulcus-shape based TMS mapping, we uncovered a centre-surround organisation of short-latency sensory integration (study 1) and traced use-dependent intra-area reorganisation in human M1-HAND (study 2). In the second part of my talk, I will touch on the concept of “temporal neuronavigation”. Using the EEG as read out of ongoing neural activity, TMS can be used to target a specific phase of an ongoing brain oscillation expressed such as slow wave oscillations during sleep or pericentral mu rhythm during wakefukness. This EEG-informed TMS approach opens up novel possibilities for informed open-loop or closed-loop applications.
Host: Lennart Verhagen
Venue: Large Lecture Theatre, dept Plant Sciences (OX1 3RB)