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Transcranial magnetic stimulation (TMS) is widely used to study the physiology of the primary motor hand area (M1-HAND) in humans. In the first part of my talk, I will describe a novel “spatial neuronavigation” approach designed to map the somatotopy of corticomotor representations in the motor hand knob. Using sulcus-shape based TMS mapping, we uncovered a centre-surround organisation of short-latency sensory integration (study 1) and traced use-dependent intra-area reorganisation in human M1-HAND (study 2). In the second part of my talk, I will touch on the concept of “temporal neuronavigation”. Using the EEG as read out of ongoing neural activity, TMS can be used to target a specific phase of an ongoing brain oscillation expressed such as slow wave oscillations during sleep or pericentral mu rhythm during wakefukness. This EEG-informed TMS approach opens up novel possibilities for informed open-loop or closed-loop applications.

Host: Lennart Verhagen

Venue: Large Lecture Theatre, dept Plant Sciences (OX1 3RB)

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