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Many of our daily activities require the use of spatial information that we maintain in our memory. For example, we successfully find our way to the office every day or we initiate movements to locate out-of-sight objects in our home because we are able to retrieve from our memory information about where things are located in the environment. In this talk, I will present results from studies that were conducted in my lab in an effort to understand the organizational structure of spatial memory. The typical paradigm we used entails encoding in memory the locations of objects in unfamiliar environments and then pointing to them from imagined perspectives. The behavioural patterns of results from these studies allowed us to draw inferences about the reference frames involved in the encoding and retrieval of spatial information under various conditions. The implications of results for theories of spatial memory as well as for the design of various modern tools (e.g., user interfaces for search-and-rescue robots, You-Are-Here maps etc.) will be discussed.