Kevin Marche
PhD
Postdoctoral Research Associate
Decision Making and Motor Control in adaptive behaviour
I am interested in understanding information processing in the prefrontal cortex, the premotor cortex, and the striatum in the context of choosing actions to obtain reward and how the midbrain dopaminergic system influences signal integration in the striatum.
My projects include three lines of investigation:
- Action selection and motor control
- Reward-guided choice behaviour in an ambiguous environment (social or economic)
- Learning processes associated with changes in action-outcome contingencies
I am using either simultaneous dual-neuron recordings, fMRI tools, or Reinforcement Learning models in behaving macaque monkeys according to project requirement.
I aim to investigate learning-related changes in neuronal activities, with an emphasis on the following aspects:
- Functional organization of the striatum and its connectivity, related to information processing
- Signal processing in Basal Ganglia neuronal microcircuit
- Social and economic values processing in fronto-striatal functional connectivity
- Cortico-striatal functional connectivity during complex decisions
Recent publications
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Social prediction modulates activity of macaque superior temporal cortex.
Journal article
Roumazeilles L. et al, (2021), Sci Adv, 7
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Activity of fast-spiking interneurons in the monkey striatum during reaching movements guided by external cues or by a free choice
Journal article
MARCHE K. and APICELLA P., (2020), European Journal of Neuroscience
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Differential functional connectivity underlying asymmetric reward-related activity in human and nonhuman primates.
Journal article
Lopez-Persem A. et al, (2020), Proc Natl Acad Sci U S A, 117, 28452 - 28462
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Accelerating the Evolution of Nonhuman Primate Neuroimaging.
Conference paper
PRIMatE Data Exchange (PRIME-DE) Global Collaboration Workshop and Consortium. Electronic address: michael.milham@childmind.org None. and PRIMatE Data Exchange (PRIME-DE) Global Collaboration Workshop and Consortium None., (2020), Neuron, 105, 600 - 603
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Changes in activity of fast-spiking interneurons of the monkey striatum during reaching at a visual target.
Journal article
Marche K. and Apicella P., (2017), J Neurophysiol, 117, 65 - 78