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We are also working in collaboration with the Department of Ophthalmology to study structural changes in the photoreceptor mosaic associated with specific inherited retinal diseases. Stargardt disease causes degeneration in the macular region of the retina, leading to central vision loss. Imaging disease progression at the cellular level will help us to understand the time-course of degeneration and, in the future, monitor the efficacy of targeted treatments, such as stem cell therapy. Using psychophysical measures we aim to understand the relationship between structural and functional changes in the diseased retina for better characterization of phenotypes and their associated genotypes.