The Feeling Safe Programme

Theoretical rationale:

Freeman, D. (2016). Persecutory delusions: a cognitive perspective on understanding and treatment. Lancet Psychiatry, 3, 685-692.

Presence of causal factors:

Freeman, D., Taylor, K., Molodynski, A., & Waite, F. (2019). Treatable clinical intervention targets for patients with schizophrenia. Schizophrenia Research, 211, 44-50.

Worry:

Freeman D, Dunn G, Startup H, Pugh K, Cordwell J, Mander H, Cernis, E., Wingham, G., Shirvell, K., & Kingdon, D. (2015) Effects of cognitive behaviour therapy for worry on persecutory delusions in patients with psychosis (WIT): a parallel, single-blind, randomised controlled trial with a mediation analysis. Lancet Psychiatry, 2, 305-313.

Negative beliefs about self:

Freeman, D., Pugh, K., Dunn, G., Evans, N., Sheaves, B., Waite, F., Cernis, E., Lister, R., & Fowler, D. (2014). An early Phase II randomised controlled trial testing the effect on persecutory delusions of using CBT to reduce negative cognitions about the self: the potential benefits of enhancing self confidence. Schizophrenia Research, 160, 186-192.

Sleep dysfunction:

Freeman, D., Waite, F., Startup, H., Myers, E., Lister, E., McInerney, J., Harvey, A., Geddes, J., Zaiwalla, Z., Luengo-Fernandez, R., Foster, R., Clifton, L, & Yu, L-M. (2015). Efficacy of cognitive behavioural therapy for sleep improvement in patients with persistent delusions and hallucinations (BEST): a prospective, assessor-blind, randomised controlled pilot study. Lancet Psychiatry, 2, 975-983.

Waite, F., Myers, E., Harvey, A., Espie, C., Startup, H., Sheaves, B., & Freeman, D. (2016). Treating sleep problems in patients with schizophrenia. Behavioural and Cognitive Psychotherapy, 44, 273-287. 

Freeman, D., Sheaves, B., Goodwin, G., Yu, L-M., Nickless, A., Harrison, P., Emsley, R., Luik, A., Foster, R., Wadekar, V., Hinds, C., Gumley, A., Jones, R., Lightman, S., Jones, S., Bentall, R., Kinderman, P., Rowse, G., Brugha, T., Blagrove, M., Gregory, A., Fleming, L., Walklet, E., Glazebrook, Davies, E., Hollis, C., Haddock, G., John, B., Coulson, M., Fowler, D., Pugh, K., Cape, J., Mosely, P., Brown, G., Hughes, C., Obonsawin, M., Coker, S., Watkins, E., Schwannauer, M., MacMahon, K., Siriwaardena, A., Espie, C. (2017). The effects of improving sleep on mental health (OASIS): a randomised controlled trial with mediation analysis. Lancet Psychiatry, 4, 749-758.  

Defence behaviours:

Freeman, D., Bradley, J., Antley, A., Bourke, E., DeWeever, N., Evans, N., Černis, E., Sheaves, B., Waite, F., Dunn, G., Slater, M., & Clark, D. (2016). Virtual reality in the treatment of persecutory delusions.: a randomised controlled experimental study testing how to reduce delusional conviction. British Journal of Psychiatry, 209, 62-67.

Full treatment case series:

Freeman, D., Bradley, J., Waite, F., Sheaves, B., DeWeever, N., Bourke, E., McInerney, J., Evans, N., Černis, E., Lister, R., Garety, P. & Dunn, G. (2016). Targeting recovery in persistent persecutory delusions: a proof of principle study of a new translational psychological treatment. Behavioural and Cognitive Psychotherapy, 44, 539-552.

Randomised controlled trial:

Freeman, D., Emsley, R., Diamond, R., Collett, N., Bold, E., Chadwick, E., Isham, L., Bird, J., Edwards, D., Kingdon, D., Fitzpatrick, R., Kabir, T., Waite, F., & Oxford Cognitive Approaches to Psychosis Trial Study Group (2021). Comparison of a theoretically driven cognitive therapy (the Feeling Safe Programme) with befriending for the treatment of persistent persecutory delusions: a parallel, single-blind, randomised controlled trial. Lancet Psychiatry.